HOLLYWOOD, CA – FEBRUARY 28: Recording artist Lady Gaga attends the 88th Annual Academy Awards at Hollywood & Highland Center on February 28, 2016 in Hollywood, California. (Photo by Jason Merritt/Getty Images)

Lady Gaga isn’t afraid to call out anyone on their BS – even America’s Vice President.

At a recent performance at her Las Vegas residency, Enigma, the Shallow singer took a moment to criticise Donald Trump’s right-hand man Mike Pence, whose wife Karen recently announced she is working at a Christian, anti-LGBTQ school.

“To Mike Pence, who thinks it’s acceptable that his wife works at a school that bans LGBTQ, you’re wrong,” Gaga told the crowd.

“You say we should not discriminate against Christianity? You’re the worst representation of what it means to be a Christian.

“I am a Christian woman, and what I do know about Christianity is that we bear no prejudice and everybody is welcome. So you can take all that disgrace, Mr. Pence, and can look yourself in the mirror and you’ll find it right there.”

Watch the powerful moment.